Over 90% of Quello patients report less frequent allergy symptoms after 1 year of Quello allergy drops, and over 60% have been allergy-free for more than 5 years after.

While there is no official reported success rate for sublingual immunotherapy in managing allergy symptoms, studies report that about 86% of patients who completed a full 4-year course of treatment had a significant reduction in seasonal allergy symptoms. (1, 2)

In this article, we will look at the success rate of SLIT according to research, how long it takes to work, and the overall safety of SLIT.

Sublingual Immunotherapy Success Rate

Here are some evidence-based data on the success of SLIT:

• SLIT reduced allergy symptoms by about 70%. (3)

• Some studies report an improvement of  40% to 60% in allergy symptoms (3, 4)

• About a 40% reduction in the use of allergy medication (4)

• Relieves seasonal allergy symptoms by about 30-40% (4)

• Reduced dust mite allergy symptoms by up to 70%. (3)

• The success rate of SLIT may vary with the type of allergen

• About 90% of patients with allergies are satisfied with how SLIT has helped their symptoms. (5)

What is Sublingual Immunotherapy?

Sublingual immunotherapy, also known as SLIT, is a type of allergy immunotherapy that involves placing allergy medicine under the tongue, rather than allergy shots, which are given under the skin.

There are two main types of SLIT: allergy drops and allergy tablets. Both treatments involve placing a drop or tablet under the tongue to be absorbed into the body. 

How Sublingual Immunotherapy Works

SLIT works by exposing the body to small amounts of the substance that you are allergic to. The dose given to you at the start is gradually increased over time to reduce your sensitivity to allergens and improve your tolerance to them.

Allergy therapy is currently the only treatment that modifies how your body responds to allergens, rather than just treating symptoms. (6)

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How Long Does It Take for SLIT to Work?

Studies suggest that patients achieve a prolonged and lasting reduction in allergy symptoms after 4 years of treatment.  (7) However, you may see a significant improvement in allergy symptoms after 6 to 12 months of SLIT treatment.

Over time, SLIT will help reduce the severity and frequency of allergy attacks and may even lead to an allergy-free life.  The benefits of allergy drops can last up to 25 years after completing a 4-year course of treatment.

Is SLIT safe?

SLIT is generally considered safe for both adults and children. As with all forms of allergen immunotherapy, there is a small risk of severe allergic reactions (anaphylaxis). (8)

For the above reason, SLIT should always be taken under the guidance of a qualified healthcare provider. Quello offers clinician-led care and ongoing support to help ensure allergy drops are used safely and appropriately.

Who can benefit from sublingual Immunotherapy?

Sublingual immunotherapy is for anyone tired of frequent, persistent allergy symptoms and seeking long-term relief.  If you want to learn more about how Quello allergy drops can change the course of your allergy symptoms, book a free consultation with one of our allergy specialists.

You may also benefit from SLIT if:

• You are looking for a convenient and flexible way to manage allergies

• Are scared of needles

• Conventional allergy medications like antihistamines have become less effective

• Tired of allergy attacks during pollen season

While generally safe and effective, SLIT may not be for you if you have: (4)

• History of severe allergic reaction

• Heart problems

• Uncontrolled asthma

• Certain immune disorders.

If you are unsure whether SLIT is for you, you can book a free discovery call with a Quello-licensed provider to get expert advice.

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Why Sublingual Immunotherapy May Not Work?

While effective, sublingual immunotherapy may not work if:

• You do not take your allergy drops or tablet consistently

• The SLIT formulation  contains too low a dose of the allergen extract

• Your treatment bottle is older than 6 months, leading to a reduced antigen potency

• Have mouth ulcers or recently undergone oral surgery, which may make it harder to take your drops.

• You got misdiagnosed by allergy testing, leading to receiving the wrong SLIT formulation

• You did not complete your treatment for the recommended treatment duration ( recommended 4 years)

Start Your Journey to Allergy Freedom Today with Quello

Start overcoming your allergies.

Get our free allergy test kit

If ongoing allergy symptoms are affecting your daily life and you’re looking for an alternative to frequent allergy medications, Quello allergy drop is a form of SLIT worth exploring.

Start with our free allergy test to identify your triggers, so we can create a formulation that directly addresses your symptoms. Once your results are ready, you can book a consultation with our allergists to discuss the best way to manage your allergies.